Significant results were retrieved for improved OS and PFS with combination of high infiltration with CD3+/CD8+ (OS p = 0.005, PFS p = 0.038), CD8+/CD20+ (OS p = 0.038, PFS p = 0.029), and CD20+/CD66b+ tumor-infiltrating leukocytes (OS p = 0.010, PFS p = 0.028). This evidence concerns the gene CEACAM8 and neoplasm.