Further, investigation of β-elemene on human non-small cell lung cancer A549 cells by Shu et al. explained that β-elemene inhibited the activity of the P13K/Akt/ mammalian target of rampamycin (mTor)/ribosomal protein S6 kinase beta-1(p70S6K1) signaling pathway, resulting in protective autophagy and apoptosis [50]. This evidence concerns the gene RPS6KB1 and non-small cell lung carcinoma.