To confirm whether p53 is one of the factors that regulate survivin expression in CCAR2- and Hsp60-deficient cells, we compared expression of survivin protein in SH-SY5Y (p53 wild-type and MYCN non-amplified cells) and BE(2)-M17 (p53 mutant type and MYCN amplified cells) neuroblastoma cells [40,41,42]. Here, CCAR2 is linked to neuroblastoma.