Thus, the maximal % inhibition of fluticasone propionate was 117%, 95%, 75% and 82% for IL-8, MMP9, IL-1β and GM-CSF, respectively, in neutrophils from healthy subjects, and 57%, 60%, 61% and 19%, respectively, in neutrophils from COPD patients (Fig 2A–2D and Table 2). This evidence concerns the gene IL1B and chronic obstructive pulmonary disease.