TP53 and mantle cell lymphoma: Abnormal cell and molecular genetics, such as TP53 mutations, were closely associated with the MCL prognosis.[28–30,44–47] Because the MIPI scoring system does not include the biological characteristics of tumor cells and seemingly cannot classificate low-risk and intermediate-risk groups in Asian populations, further establishment of a better MCL prognostic system in Asian populations should be taken into consideration.