PCLAF and Cognitive impairment: Studies have shown that anti-inflammatory and inhibiting the platelet-activating factor (PAF) properties of ginkgo extract (EGB761) are effective on MS disease.33,34 Ginkgolides is the major component of G. biloba, its effect on the PAF activity represents the possible therapeutic role of this plant on MS.34 PAF’s role in inflammation process is obviously introduced, so ginkgo can inhibit this process.35 In addition, ginkgo reverses cognitive impairment and reduces fatigue in MS patients.36,37G.