IGF2 and neurodevelopmental disorder: In line with our study, many previous studies also identified DNA methylation changes of genes related to metabolism in PTB cord blood [29, 30, 52], such as NCOR2, IGF2BP1, IGF2, and TET1. Additionally, we also observed DNA methylation alterations of BAIAP2 and OXTR in sPTB cord blood, which were related to neurodevelopmental disorders.