MMP2 and breast carcinoma: Moreover, miquelianin interferes with the protein-protein interaction of Aβ (1–40) and Aβ (1–42) [44], and inhibits the noradrenaline-promoted invasion of MDA-MB-231 human breast cancer cell by regulating the β2-adrenergic signaling pathway through matrix metalloproteinase-2 (MMP2) and matrix metalloproteinase-9 (MMP9) [45].