SOD1 and type 2 diabetes mellitus: It has been found that administration of probiotics (300 g/day) containing L. acidophilus La5 and B. lactis Bb12 or traditional yogurt (300 g/day) for 6 weeks results in significant increase in the activity of both erythrocyte SOD and GPx in type 2 diabetes mellitus (T2DM) patients [58].