BRCA2 and ovarian cancer: In conclusion, we confirmed a frequency of P and LP variants in BRCA1 and BRCA2 in patients with ovarian carcinoma slightly above the expected for European and US populations but smaller than shown by Asian studies, demonstrating the specific genetic characteristics of Brazilian ovarian cancer patients who present a high frequency of the c.5266dupC (p.Gln1756Profs*74) variant and one not previously described variant.