Figure 2 shows that, Serum lactate dehydrogenase activity was significantly increased (p <0.001)in both ischemic, hypertension and diabetic groups compared with the control group while serum creatine kinase (CK-BB) showed a higher values in both hypertension and diabetic groups compared to control and stroke groups (p <0.001 and <0.001). The gene discussed is CKB; the disease is Stroke.