To investigate whether ZNF443, TNFSF13B, COL2A1, and TMX1 are involved in the antrocin induction of the susceptibility of PCa cells to radiation, specific lentivirus-delivered shRNA against ZNF443, TNFSF13B, COL2A1, and TMX1 genes were used to knockdown the respective genes. The gene discussed is ZNF443; the disease is posterior cortical atrophy.