ZFP57 and transient neonatal diabetes mellitus: In humans, the phenotype associated with mutations in ZFP57 is even milder, since, in homozygous recessive patients with transient neonatal diabetes mellitus (TNDM), a form of multilocus imprinting disturbance (MLID), ZFP57 influences only a minority of imprinted differentially methylated regions (DMRs) (Boonen et al. 2013; Court et al. 2013; Bak et al. 2016).