PIK3CA and cancer: KEGG pathway enrichment analysis revealed that the targets of upregulated DE-miRNAs were enriched in pathways in cancer, PI3K-Akt signaling pathway, HTLV-I infection, endocytosis and microRNAs in cancer, whereas the targets of downregulated DE-miRNAs were enriched in pathways in cancer, microRNAs in cancer, PI3K-Akt signaling pathway, HTLV-I infection and proteoglycans in cancer.