CDKN1A and hepatocellular carcinoma: For example, exosomal miR-93-5p enhances proliferation and invasion of HCC via suppression of TIMP2/TP53INP1/CDKN1A [36]; miR-93-5p promotes HCC proliferation and epithelial–mesenchymal transition (EMT)-mediated invasion and metastasis by directly targeting PDCD4 [37].