AMACR and posterior cortical atrophy: A central role for fatty acid oxidation in supplying energy to the PCa cell is supported by the observation that the peroxisomal enzyme α-methylacyl-CoA racemase (AMACR), which facilitates the transformation of branched-chain fatty acids to a form suitable for β-oxidation, is highly overexpressed in PCa compared with normal prostate [286–288].