This is also corroborated by Xiao et al. [74], which reported that the m6A methyltransferase METTL3 acted as a tumor suppressor in renal cell carcinoma and publications in [75, 76], which identified YTHDF2, an m6A binding protein, to be involved in renal cell carcinoma. This evidence concerns the gene METTL3 and hereditary clear cell renal cell carcinoma.