CEBPA and colitis: To explore the function of C/EBPα in tumor progression, mice with conditional loss-of-function alleles of C/EBPα (C/EBPαFlox/Flox-VilinCreERT2) were compared to controls (C/EBPαFlox/Flox) in a chemically induced intestinal azoxymethane–dextran sodium sulfate (AOM-DSS) colitis-associated carcinogenesis model (Bollrath et al, 2009).