Initial reports of KCNJ11 PNDM showed that ≈20% of affected individuals exhibited overt and severe neurological features in addition to their diabetes; this was named DEND syndrome (developmental delay, epilepsy, and neonatal diabetes) or intermediate DEND (iDEND) if epilepsy was not evident in the first 12 months of life. The gene discussed is KCNJ11; the disease is epilepsy.