Hepatobiliary nuclear scintigraphy using Tc-99m-DISIDA with cholecystokinin (DISIDA with CCK injection) has to be performed to estimate the gallbladder ejection fraction, in accordance with the standard calculation of gallbladder contraction 30 minutes after CCK injection, to establish the possible relationship of gallbladder dysfunction and chronic diarrhea. The gene discussed is CCK; the disease is Gallbladder dysfunction.