The principal observations and conclusions are: (1) NPs increase MDA-MB-231LUC+ chemokinesis, both migration and invasion in this cellular line, (2) NPs alter and primarily increase the expression of all their receptors within the same time frame, and (3) NPs increase the acute release of kininogen (HMWK), molecule with pro-nociceptive and pro-tumorigenic functions, from these cancer cells. The gene discussed is KNG1; the disease is cancer.