sAJM589 also showed a dose-dependent inhibition of various Myc-dependent cancer cell lines: Ramos (Burkitt’s lymphoma), HL-60 and KG1a (acute myeloid leukemia) with IC50s of 0.9, 1.2, and 0.8 μM, respectively, but had no effect on resting macrophages whose proliferation is independent of Myc activity. Here, MYC is linked to Burkitt lymphoma.