In PCa, the three Myc paralogs are most frequently amplified and implicated in the pathogenesis and progression across its full spectrum, from localized adenocarcinoma (L-Myc) to the most advanced and treatment-resistant subtypes—castration-resistant (c-Myc) and its neuroendocrine phenotype (N-Myc) [137,138,139,140,141,142,143,144]. This evidence concerns the gene MYC and posterior cortical atrophy.