Their biological activity interferes with tumor angiogenesis by blocking the intracellular signaling cascades of various soluble molecules that are involved in the growth of new blood vessels, such as VEGF (Vascular Endothelial Growth Factor), PDGF (Platelet-Derived Growth Factor), c-Kit-ligand, and FLT-3 (Fms Related Tyrosine Kinase 3) [1]. This evidence concerns the gene VEGFA and neoplasm.