Common and rare variants implicated in schizophrenia, ASD, and ID are also enriched for RBFOX targets.7,54,60–63 Furthermore, RBFOX1 copy number variants have been reported in ASD64 whereas RBFOX1 common variants have recently been shown to confer increased risk of schizophrenia.7 The gene set of differentially spliced genes in ZNF804A-depleted cells was also enriched for common variant alleles associated with schizophrenia, bipolar disorder and schizophrenia, and ASD. This evidence concerns the gene RBFOX1 and bipolar disorder.