In the novel locus, there are three genes, DNAH10, ZNF664 and CCDC92, which are believed to be associated with multiple CAD risk factors such as high-density lipoprotein cholesterol level, triglycerides levels and waist-to-hip ratio [33–35] Here, B-LORE prioritized three SNPs (rs1187415, rs7961449 and rs6488913) in a region with strong LD. The gene discussed is ZNF664; the disease is coronary artery disorder.