Table 1 [12, 50–71, 74, 98–101, 110–117] summarizes the available data regarding the distribution of HLA alleles and MRI findings for five demyelinating syndromes: clinically definite MS, AQP4-positive NMOSD, MOG antibody associated disorders, and antibody-negative ADEM. The gene discussed is AQP4; the disease is acute disseminated encephalomyelitis.