On the other hand, it has the set integrated by hsa-mir-375, hsa-mir-15a, hsa-mir-212, hsa-mir-92b, hsa-mir-15b and hsa-mir-185-3p, are reported as associated with mRNA-Smad7 in other types of cancer or malignancies and their cumulative relative importance of 23%. The gene discussed is SMAD7; the disease is cancer.