Therefore, we examined the potential participation of c-Abl, B-cell lymphoma-2 (bcl-2), caspase-9, caspase-3 and PARP in the cisplatin-induced MLH1/c-Abl apoptosis signaling pathway in endometrial carcinoma cells via Western blot analysis. The gene discussed is CASP9; the disease is endometrial carcinoma.