KDM1A and glioblastoma: 2009; Lim et al. 2010), but required concentrations up to 20‐fold higher than the IC50 for 2‐PCPA (20.7 μM). Similarly, high concentrations of 2‐PCPA have been shown to be ineffective against other immortal GBM cultures, despite high LSD1 protein levels (Singh et al. 2011). Q‐PAC not only performed better than 2‐PCPA against GBM viability, but also reduced the migration and invasion phenotype of U87 cultures. Aggressive migration and invasion are key treatment challenges of GBM tumours (Demuth and Berens 2004).