According to a research published, TRAIL may also simultaneously trigger some other signals that regulate liver fibrosis, because NK cells carrying TRAIL are capable of mediating inactivation of HSCs.37 However, the inactivation of HSCs is said to be associated with up‐regulation of some antiapoptotic genes,38 which means aHSC apoptosis is negatively correlated with HSC inactivation. This evidence concerns the gene TNFSF10 and Hepatic fibrosis.