MAPK8 and neuroblastoma: A similar strategy was applied to the dynamics of JNK network and successfully predicted survival of neuroblastoma patients.14 Dynamics of key factors in apoptotic signalling pathways also showed a high predictive value on fractional cell killing in response to chemotherapies or antibodies.39,40 Here we assumed that secretion descriptors of IFN-γ are related to the functionality and adaptability of host immune system.