Procalcitonin (PCT), C-reactive protein (CRP), Interleukin 6 (IL-6), Interleukin 8 (IL-8), Interleukin 18 (IL-18), Human neutrophil gelatinase (NGAL) and Adrenomedullin (ADM) have been widely used, but even these have limited capacity to distinguish sepsis from other inflammatory conditions, or to predict clinical outcomes. The gene discussed is ADM; the disease is Sepsis.