In addition, in patients with advanced stages of lung cancer, the expression of TNFAIP8 in tumor-infiltrating CD8+ T cells is lower compared to patients with primary stages of lung cancer, suggesting that TNFAIP8 may be involved in the progression of non-small cell lung cancer (NSCLC) [71]. This evidence concerns the gene TNFAIP8 and non-small cell lung carcinoma.