TNFAIP8 and prostate cancer: In prostate cancer, TNFAIP8 is a potential biomarker [70], and depletion of TNFAIP8 increases expression of genes associated with anti-proliferation and apoptosis, for example, IL24, FAT3, LPHN2, and EPHA3. TNFAIP8 depletion also increases the expression of fatty-acid oxidation gene, ACDL, and decreases the expression of several oncogenes such as NFAT5, MALAT1, MET, FOXA1, KRAS, S100P, and OSTF1 [12].