TTPA and parasitic infectious disease: When α-TTP knockout and wild type mice were infected with P. berghei NK65, the mRNA expression of MIF increased dramatically in the bone marrow and spleen during the peak of parasitemia in wild type mice, but not in α-TTP knockout mice [24], hence suggesting that hemozoin might be a key factor in the inhibition of erythropoiesis, as described previously [47].