SQSTM1 and tuberculosis: In a dose response assay, we found that the HSF1 inhibitor KRIBB11 (I-HSF1) used at 5 μM was able to reduce HSF1 activity, as revealed by the decreased expression of its target heat shock protein (HSP) 70 (Figure 6A), and reduced p62/SQSTM1 and K-bZIP expression in TB- or BZ-treated PEL cell lines (Figure 6B).