Activated NK cells play an important role in attenuating liver cirrhosis by killing hepatic stellate cells (HSCs).22 We cultured NK cells with or without purified gMDSCs from ALD patients and found that a decreased percentage of NK cells cultured with gMDSCs expressed tumour necrosis factor‐related apoptosis‐inducing ligand (TRAIL) compared to those cultured without gMDSCs. Here, TNFSF10 is linked to cirrhosis of liver.