Huntington's disease (HD) is a fatal, incurable autosomal dominant neurodegenerative disorder caused by instable expansion of polyglutamine (polyQ) tract within the resulting mutated HTT protein (mHTT).1 Huntington's disease pathology is characterized by a massive loss of neurons in the striatal part of the basal ganglia2 that consequently causes motor and cognitive dysfunction. This evidence concerns the gene HTT and juvenile Huntington disease.