In view of the fact that miR-424-3p can reduce the expression of galectin-3 (the anti-apoptotic protein associated with cancers chemoresistance) and, on the other hand, sensitize chemoresistant non-small-cell lung cancer cells to cisplatin, we hypothesized that transfection of miR-424-3p which mimic into ovarian cancer cells will sensitize them to cisplatin, what will be achieved by reducing the expression of galectin-3. This evidence concerns the gene LGALS3 and ovarian cancer.