In sodium iodate-induced retinal degeneration rats, 7 days after NaIO3 injection, the upregulated VEGF protein expressions were observed mainly on RPE cells compared with that of untreated control group (Figure 8(c)), and pretreatment with kaempferol decreased the upregulated VEGF protein expressions in sodium iodate-induced retinal degeneration rats. The gene discussed is VEGFA; the disease is retinal degeneration.