CEACAM5 and familial pancreatic carcinoma: The present study exhibits certain advantages: (1) the study compared the diagnostic value of CA 19-9 and CEA for the detection of pancreatic cancer directly; (2) the ratios of sensitivity, specificity, DOR, and AUC were investigated in order to allow a direct comparison of the diagnostic value of CA 19-9 and CEA; (3) the diagnostic value of CA 19-9 and CEA, based on different cutoff values, was further explored; and (4) the large sample size allowed us to quantitatively evaluate the diagnostic value of CA 19-9 and CEA.