The results found that, compared with the normal tissues, miR-200c expression was significantly higher in EEC tissues (92.50%, 37/40), and the expression of PTEN and PTENP1 was lower (PTEN, 67.6%, 25/37, and PTENP1, 92.6%, 25/27), though there were three cases in which expression of PTEN was negative in the both cancer and adjacent normal tissues, and in 13 cases PTENP1 were neither expressive in the both areas (Fig. 1a–d). Here, PTENP1 is linked to cancer.