The 15q11.2 BP1-BP2 region is adjacent to the areas affected in the Prader-Willi and Angelman syndromes, conditions resulting from deletions of the BP1-BP3 (type I) or the BP2–BP3 (type II) regions at 15q11.2, with the BP1-BP2 deletion partly overlapping the type I but not type II Prader-Willi/Angelman region. Here, IGFBP2 is linked to Angelman syndrome.