Additionally, the enrichment of activated leukocyte cell adhesion molecule (ALCAM), cathepsin S, CD26, CD44, interleukin 1 receptor 2 (IL1R2), macrophage migration inhibitory factor (MIF), and thymus and activation regulated chemokine (TARC) in the plasma of HL patients has been correlated with lymphoma progression [90]. This evidence concerns the gene MIF and lymphoma.