F7 and thrombophilia: Data regarding Factor VII and its ability to predict kidney dysfunction are scarce; however, it is well established as a marker of hypercoagulability and persistence of inflammatory response.32 In a community‐based cohort of 588 elderly individuals, Fried et al found that elevations in CRP (P < 0.001), white blood count (P < 0.001), fibrinogen (P < 0.001), and Factor VII (P < 0.001) were associated with a subsequent rise in serum creatinine.