PPARG and obesity due to melanocortin 4 receptor deficiency: The distribution of genotypes of most obesity-predisposing SNPs was concordant with the Hardy-Weinberg equilibrium principle, except for rs1386835 (PPARG), rs17782313 (MC4R), rs2287019 (QPCTL), and rs3813929 (HTR2C), as shown in Supplementary Table 1.