Fig. 5 also shows that re-positioning the animals resulted in significantly different measurements of haemoglobin content and blood sO2 levels. A trend for an increase in ROI-averaged Hb, HbO2 and HbT was observed for most animals over time, independent of the starting and ending angle of the tumour relative to the transducer. ROI-averaged blood sO2 tended to increase for animals 3 and 4 but remain more constant for animals 1 and 2. Here, GSTM1 is linked to neoplasm.