ZRANB3 and peanut allergic reaction: STALs with the peanut allergen Ara h2 (Ah2) and a high affinity Siglec-2 ligand (modified α2,6 linked sialic acid) incorporated in the outer membrane have shown high binding affinity to the B cell receptor and Siglec-2 simultaneously and to prevent peanut allergy against the Ah2 allergen in mice (109) (Figure 4E).