CRP and bacterial infectious disease with sepsis: In a recent investigation in which the diagnostic characteristics of the PCT assay, CRP concentrations, WBC counts, and ANC counts for the detection of SBIs were evaluated, it was shown that although the area under the ROC curves for CRP and PCT were similar (AUC 0.81, 95% CI: 0.83–0.99 vs. AUC 0.80, 95% CI: 0.75–0.85; p = 0.70), PCT could more accurately detect bacteremia and bacterial meningitis (AUC 0.91, 95% CI: 0.83–0.99 vs. AUC 0.77, 95% CI: 0.65–0.89, p = 0.002) [52].