EMC disruption has also been observed to affect phospholipid trafficking (Janer et al., 2016; Lahiri et al., 2014), autophagosome formation (EMC6, Li et al., 2013; Shen et al., 2016), neurological degeneration (EMC1, Harel et al., 2016), retinal dystrophy (EMC1, Abu-Safieh et al., 2013), SV40 egress from the ER (EMC1, Bagchi et al., 2016), and pathogenesis of flaviviruses including West Nile, Dengue and Zika (Le Sommer et al., 2012; Ma et al., 2015; Marceau et al., 2016; Savidis et al., 2016; Zhang et al., 2016). Here, EMC1 is linked to dengue disease.