The HSPB family, in particular HSP27, has been shown to be associated with several human cancers, as it promotes epithelial to mesenchymal transition (EMT) [13], [14], blocks apoptotic signalling [15], and triggers activation of oncogenic transcription factors such as NF-κB [13] and mitogen activated protein kinases (MAPK) [16], independent of their ATP hydrolysis function [17]. The gene discussed is HSPB1; the disease is cancer.