INS and type 1 diabetes mellitus: Daily prandial insulin dose were lower in CHI patients with diabetes both, at diabetes onset (8.5 IE [2–12] vs. 10.8 IE [5.9–18.5] in patients with T1DM, p = 0.07) and at follow-up (22 IE [10–33.5] vs. 28 IE [18–38.8] in patients with T1DM, p = 0.05) (Fig. 6d).